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Treatment of COVID-19: a review of current and prospective pharmacotherapies.

Quek, Eleanor; Tahir, Hasan; Kumar, Poornima; Hastings, Robert; Jha, Rajeev.

Br J Hosp Med (Lond) ; 82(3): 1-9, 2021 Mar 02.

Article in English | MEDLINE | ID: covidwho-1168180

ABSTRACT

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and have grave health and socioeconomic consequences worldwide. Researchers have raced to understand the pathophysiological mechanisms underpinning the disease caused by SARS-CoV-2 so that effective therapeutic targets can be discovered. This review summarises the key pharmacotherapies that are being investigated for treatment of COVID-19, including antiviral, immunomodulator and anticoagulation strategies.

Subject(s)

Anticoagulants/therapeutic use , Antiviral Agents/therapeutic use , COVID-19 Drug Treatment , Glucocorticoids/therapeutic use , Immunologic Factors/therapeutic use , Platelet Aggregation Inhibitors/therapeutic use , Adenosine Monophosphate/analogs & derivatives , Adenosine Monophosphate/therapeutic use , Alanine/analogs & derivatives , Alanine/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Azetidines/therapeutic use , COVID-19/therapy , Colchicine/therapeutic use , Dexamethasone/therapeutic use , Humans , Immunization, Passive , Ivermectin/therapeutic use , Janus Kinase Inhibitors/therapeutic use , Purines/therapeutic use , Pyrazoles/therapeutic use , SARS-CoV-2 , Sulfonamides/therapeutic use , COVID-19 Serotherapy

ABSTRACT

Subject(s)

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